Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495212 | 1.00 | MEN1 (0.42) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL8938839 | 0.94 | PTGS2 (0.36) | MEN1KMT2ACYP3A4TUBB4ATUBB | |
| SCHEMBL5188491 | 0.92 | HSD17B1 (0.42) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL19607444 | 0.85 | ACHE (0.42) | MEN1KMT2AKDM4EALDH1A1ACHE | |
| SCHEMBL29420327 | 0.83 | KMT2A (0.56) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL29420326 | 0.83 | KMT2A (0.56) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL354177 | 0.83 | KMT2A (0.56) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL15931767 | 0.75 | HPGD (0.44) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL1561740 | 0.75 | HTR2A (0.51) | MEN1KMT2AKDM4EALDH1A1TUBB4A | |
| SCHEMBL2306816 | 0.75 | HTR2A (0.51) | MEN1KMT2AKDM4EALDH1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019560-A1 | DEUTERATED DERIVATIVES OF DONEPEZIL | CONCERT PHARMACEUTICALS INC. (US) | 2010-02-18 | — | — | WO | disclosed |