Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 15/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495215 | 0.92 | FFAR4 (0.41) | LIPECHRM4 | |
| SCHEMBL734982 | 0.89 | LIPE (0.43) | LIPECHRM4KCNA5 | |
| SCHEMBL734983 | 0.89 | LIPE (0.43) | LIPECHRM4KCNA5 | |
| SCHEMBL734076 | 0.88 | LIPE (0.41) | LIPECHRM4KCNA5 | |
| SCHEMBL734077 | 0.88 | LIPE (0.41) | LIPECHRM4KCNA5 | |
| SCHEMBL13495214 | 0.82 | HTR7 (0.44) | — | |
| SCHEMBL736803 | 0.81 | NOTUM (0.39) | LIPECHRM4 | |
| SCHEMBL736804 | 0.81 | NOTUM (0.39) | LIPECHRM4 | |
| SCHEMBL734801 | 0.80 | CHRM4 (0.39) | LIPECHRM4 | |
| SCHEMBL734800 | 0.80 | CHRM4 (0.39) | LIPECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012619-A1 | DIAZEPAN AND PIPERAZINE DERIVATIVES MODULATORS OF CHEMOKINE RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-02-04 | — | — | WO | disclosed |