Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495584 | 0.89 | HPGD (0.58) | ALDH1A1HPGDSMN1; SMN2KDM4EHTT | |
| SCHEMBL13495641 | 0.79 | HPD (0.47) | HPGDSMN1; SMN2HTTKMT2AHRH3 | |
| SCHEMBL13495693 | 0.78 | TSHR (0.49) | ALDH1A1SMN1; SMN2KDM4EHTTTSHR | |
| SCHEMBL13666386 | 0.77 | NPC1 (0.50) | ALDH1A1HPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL13495640 | 0.77 | HRH3 (0.51) | SMN1; SMN2HRH3 | |
| SCHEMBL13495586 | 0.77 | PIK3CA (0.60) | HPGDSMN1; SMN2HRH3LMNA | |
| SCHEMBL13666581 | 0.75 | HSD17B10 (0.61) | SMN1; SMN2HTT | |
| SCHEMBL5208543 | 0.74 | EPHX2 (0.77) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPT | |
| SCHEMBL21644139 | 0.73 | DYRK1A (0.66) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPT | |
| SCHEMBL13666631 | 0.73 | POLB (0.52) | ALDH1A1SMN1; SMN2MAPTHTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |