Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13666337 | 0.85 | MAPT (0.47) | HPDPOLBPIK3CAMTORSMN1; SMN2 | |
| SCHEMBL13495586 | 0.85 | PIK3CA (0.60) | HPDHSD17B10POLBPIK3CAMTOR | |
| SCHEMBL13495640 | 0.85 | HRH3 (0.51) | HPDHSD17B10POLBPIK3CAMTOR | |
| SCHEMBL13666581 | 0.83 | HSD17B10 (0.61) | HPDHSD17B10POLBPIK3CAMTOR | |
| SCHEMBL13495748 | 0.82 | PIK3CA (0.54) | POLBPIK3CAMTORGSRPIK3CD | |
| SCHEMBL14000496 | 0.81 | MAPK1 (0.64) | HSD17B10HTTHRH3 | |
| SCHEMBL13495653 | 0.79 | MAPK1 (0.66) | HSD17B10POLBPIK3CAMTORSMN1; SMN2 | |
| SCHEMBL13495638 | 0.79 | PTGS2 (0.47) | POLBKMT2AGSRACSS2 | |
| SCHEMBL13495643 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2KMT2AHTTHRH3HPGD | |
| SCHEMBL3052790 | 0.79 | MAPK1 (0.65) | HSD17B10POLBPIK3CAMTORSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |