Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945260 | 0.82 | CA12 (0.56) | HPGDLMNACA12CA1CA2 | |
| SCHEMBL13498486 | 0.82 | PARP10 (0.50) | PARP10CNR2HDAC8CA12CA1 | |
| SCHEMBL7362723 | 0.82 | HPGD (0.63) | HPGDLMNAMAPTMEN1KMT2A | |
| SCHEMBL391547 | 0.81 | MEN1 (0.71) | PARP10HPGDLMNAMAPTMEN1 | |
| SCHEMBL13945262 | 0.81 | CA12 (0.55) | HPGDLMNACA12CA1CA2 | |
| SCHEMBL14456118 | 0.80 | PARP10 (0.55) | PARP10HDAC8SMN1; SMN2MAOBALKBH1 | |
| SCHEMBL5382299 | 0.80 | LMNA (0.43) | HPGDLMNACA12CA1CA2 | |
| SCHEMBL3604210 | 0.79 | MAOB (0.55) | PARP10HPGDLMNACA12CA1 | |
| SCHEMBL13498482 | 0.78 | PARP10 (0.53) | PARP10HDAC8SMN1; SMN2MAOBALKBH1 | |
| SCHEMBL14456120 | 0.78 | PARP10 (0.53) | PARP10HDAC8SMN1; SMN2MAOBALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036054-A1 | NOVEL SURFACE ACTIVE POLYMERIC SYSTEMS | UNIVERSITY OF DURHAM (GB) | 2010-02-11 | — | — | US | disclosed |