Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498485 | 0.80 | PARP10 (0.55) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26702121 | 0.79 | CA1 (0.54) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13945260 | 0.78 | CA12 (0.56) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL391547 | 0.77 | MEN1 (0.71) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13945262 | 0.77 | CA12 (0.55) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5378369 | 0.76 | GPBAR1 (0.38) | SMN1; SMN2MEN1KMT2ACYSLTR1TSHR | |
| SCHEMBL15276157 | 0.75 | CA12 (0.54) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5177852 | 0.75 | MRGPRX4 (0.50) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2256044 | 0.75 | SMPD1 (0.59) | LMNAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL183994 | 0.74 | LMNA (0.70) | LMNAHPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205428-B2 | Thioether derivatives, their method for production and use | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) | 2007-04-17 | — | — | US | disclosed |
| EP-1219667-B1 | Novel thioether derivatives, their method for production and use | COMM RES LAB INDEPENDENT ADMIN (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-6630578-B2 | Which respond immediately by emission of light when stimulated with light or electric energy, and are useful as switching material of memory | COMMUNICATIONS RESEARCH LABORATORY, INDEPENDENT ADMINISTRATIVE INSTITUTION (JP) | 2003-10-07 | — | — | US | disclosed |
| US-20030171507-A1 | Novel thioether derivatives, their method for production and use | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1219667-A2 | Novel thioether derivatives, their method for production and use | Communications Research Laboratory, Independent Administrative Institution (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20020072583-A1 | Novel thioether derivatives, their method for production and use | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) | 2002-06-13 | — | — | US | disclosed |