Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | GCK | P35557 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183994 | 0.97 | LMNA (0.70) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL29788280 | 0.95 | LMNA (0.65) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL340311 | 0.95 | LMNA (0.65) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL90412 | 0.92 | LMNA (0.69) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL3129603 | 0.92 | MEN1 (0.74) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL29475634 | 0.92 | LMNA (0.69) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL9323928 | 0.92 | LMNA (0.60) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL2650902 | 0.92 | LMNA (0.60) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL7362723 | 0.91 | HPGD (0.63) | MEN1KMT2ALMNAHPGDMAOB | |
| SCHEMBL2808656 | 0.90 | LMNA (0.59) | MEN1KMT2ALMNAHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9201001-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2015-12-01 | — | — | US | disclosed |
| US-9201001-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2015-12-01 | — | — | US | disclosed |
| US-20140357894-A1 | VISUAL DETECTION OF FLUORIDE IONS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2014-12-04 | — | — | US | disclosed |
| US-20140357894-A1 | VISUAL DETECTION OF FLUORIDE IONS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2014-12-04 | — | — | US | disclosed |
| US-8828735-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2014-09-09 | — | — | US | disclosed |
| US-8828735-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2014-09-09 | — | — | US | disclosed |
| EP-2049459-B1 | NOVEL PROCESS FOR THE SYNTHESIS OF (E)-STILBENE DERIVATIVES WHICH MAKES IT POSSIBLE TO OBTAIN RESVERATROL AND PICEATANNOL | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-10-02 | — | — | EP | disclosed |
| EP-2202215-B1 | Novel process for the synthesis of (E)-Stilbene derivatives which makes it possible to obtain resveratrol and piceatannol | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-10-02 | — | — | EP | disclosed |
| US-8101804-B2 | Process for the synthesis of (E)-stilbene derivatives which makes it possible to obtain resveratrol and piceatannol | CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) | 2012-01-24 | — | — | US | disclosed |
| EP-2202215-A2 | Novel process for the synthesis of (E)-Stilbene derivatives which makes it possible to obtain resveratrol and piceatannol | Clariant Specialty Fine Chemicals (France) (FR) | 2010-06-30 | — | — | EP | disclosed |
| US-6656971-B2 | Non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilins; inhibiting their peptidyl-prolyl isomerase activity; treating variety of medical conditions | GUILFORD PHARMACEUTICALS INC. | 2003-12-02 | — | — | US | disclosed |
| EP-1360173-A2 | TRISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIR USE | GUILFORD PHARMACEUTICALS INC. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020165275-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | GUILFORD PHARMACEUTICALS INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002059080-A2 | TRISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIR USE | GUILFORD PHARMACEUTICALS INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| US-5863947-A | Phenylglycine derivatives useful for treating disorders of the central nervous system | ELI LILLY AND COMPANY LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |
| EP-0807621-A1 | Derivatives of phenylglycine and use thereof as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1997-11-19 | — | — | EP | disclosed |
| US-5446189-A | Diester intermediates for diacid enzyme inhibitor | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |
| US-5041516-A | Macromolecules | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357894-A1 | VISUAL DETECTION OF FLUORIDE IONS | HNRNPL, HNRNPLL, ARAF | MEN1 3189/4885KMT2A 1693/4885LMNA 1059/4885 |
| US-20020165275-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | FKBP2, PPIG, FKBP8 | MEN1 4867/4885KMT2A 4618/4885LMNA 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.