SCHEMBL13498596

SCHEMBL13498596

[N-]=[N+]=NCCOCCOCCOCC(=O)NCCCCC(NC(=O)COCCOCCOCCN=[N+]=[N-])C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.49
▸ C3AR1 Q16581 2/20 0.42
▸ ALB P02768 8/20 0.41
▸ FOLH1 Q04609 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13936446 1.00 GLP1R (0.49) GLP1RC3AR1ALBFOLH1
SCHEMBL13936441 1.00 GLP1R (0.49) GLP1RC3AR1ALBFOLH1
SCHEMBL13936443 1.00 GLP1R (0.49) GLP1RC3AR1ALBFOLH1
SCHEMBL13936440 1.00 GLP1R (0.49) GLP1RC3AR1ALBFOLH1
SCHEMBL14547440 0.90 GLP1R (0.42) GLP1RC3AR1ALB
SCHEMBL13498595 0.89 GLP1R (0.41) GLP1RC3AR1ALB
SCHEMBL24630340 0.86 GLP1R (0.49) GLP1RALBFOLH1
SCHEMBL29072106 0.86 GLP1R (0.49) GLP1RALBFOLH1
SCHEMBL3485145 0.83 GLP1R (0.50) GLP1RALBFOLH1
SCHEMBL3485150 0.83 GLP1R (0.50) GLP1RALBFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100028939-A1 Use of Galactose Oxidase for Selective Chemical Conjugation of Protractor Molecules to Proteins of Therapeutic Interest NOVO NORDISK HEALTHCARE A/G (CH) 2010-02-04 — — US disclosed
US-20090240028-A1 Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides NOVO NORDISK A/S (DK) 2009-09-24 — — US disclosed
US-20090240028-A1 Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides NOVO NORDISK A/S (DK) 2009-09-24 — — US disclosed
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers NOVO NORDISK A/S (DK) 2009-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240028-A1 Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides VIP, PTMS, PDGFA GLP1R 103/4885C3AR1 913/4885ALB 1237/4885
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers INSR, IAPP, IGF1R GLP1R 14/4885C3AR1 3234/4885ALB 149/4885
US-20100028939-A1 Use of Galactose Oxidase for Selective Chemical Conjugation of Protractor Molecules to Proteins of Therapeutic Interest GALE, GALNT2, GALNT1 GLP1R 2352/4885C3AR1 959/4885ALB 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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