SCHEMBL13502049

SCHEMBL13502049

Cc1cc2c(cc1Cl)c1cc(Cl)c(C)cc1p2-c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CD44 P16070 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MEN1 O00255 3/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ PKM P14618 2/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ ADORA1 P30542 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ CYP3A4 P08684 1/20 0.31
▸ MAPT P10636 3/20 0.31
▸ L3MBTL1 Q9Y468 2/20 0.31
▸ THRB P10828 1/20 0.31
▸ TP53 P04637 1/20 0.30
▸ TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13502048 0.78 ACHE (0.35) ALDH1A1MEN1KMT2ATSHR
SCHEMBL13502315 0.74 TSHR (0.41) ALDH1A1HPGDMEN1KMT2ALMNA
SCHEMBL13502060 0.73 — —
SCHEMBL13502079 0.72 CYP1A2 (0.39) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL13502073 0.71 TTR (0.41) ALDH1A1HPGDRAB9ALMNAMAPT
SCHEMBL13502075 0.71 APP (0.38) ALDH1A1HPGDMEN1KMT2ANPC1
SCHEMBL13502076 0.70 ALDH1A1 (0.40) ALDH1A1HPGDMEN1KMT2ANPC1
SCHEMBL753503 0.70 KDM4E (0.30) ALDH1A1HPGDMEN1KMT2A
SCHEMBL13502068 0.69 KDM4E (0.30) ALDH1A1HPGDLMNA
SCHEMBL13502066 0.69 POLB (0.40) ALDH1A1HPGDMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 — — US disclosed
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 — — US disclosed
EP-2067807-A1 New polymer and polymer light-emitting device using the same Sumitomo Chemical Company, Limited (JP) 2009-06-10 — — EP disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 — — US disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CRY1, ARCN1, CORO1A CD44 2986/4885ALDH1A1 272/4885HPGD 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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