SCHEMBL1350340

SCHEMBL1350340

O=Cc1ccccc1CCl

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
THRB P10828 1/20 0.55
BLM P54132 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 6/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 2/20 0.44
TRIM24 O15164 2/20 0.44
TRIM33 Q9UPN9 2/20 0.44
GAA P10253 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
ERN1 O75460 2/20 0.37
SRC P12931 1/20 0.35
CYP2A6 P11509 3/20 0.35
IMPDH2 P12268 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10886670 0.82 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL7453987 0.80 LMNA (0.60) LMNAKMT2AMEN1THRBBLM
SCHEMBL10824460 0.79 ERN1 (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL29955984 0.79 ERN1 (0.42) LMNAKMT2AMEN1THRBBLM
SCHEMBL30046638 0.79 ERN1 (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL28610626 0.79 KMT2A (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL224815 0.78 LMNA (0.57) LMNAKMT2AMEN1THRBBLM
SCHEMBL29897321 0.78 LMNA (0.57) LMNAKMT2AMEN1THRBBLM
SCHEMBL9768537 0.77 KMT2A (0.39) LMNAKMT2AMEN1THRBBLM
SCHEMBL23829658 0.76 LMNA (0.55) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028904-A Biomass antibacterial composite membrane material and preparation method thereof 袁旭 2022-09-09 CN claimed
EP-2727901-B1 METHOD FOR PRODUCING 2-CHLOROMETHYLBENZALDEHYDE SUMITOMO CHEMICAL CO (JP) 2019-07-31 EP claimed
CN-103649034-B Method for producing 2-chloromethylbenzaldehyde, composition containing 2-chloromethylbenzaldehyde, and method for storing same SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-11-25 CN claimed
US-9029606-B2 Method for producing 2-chloromethylbenzaldehyde, 2-chloromethylbenzaldehyde-containing composition, and method for storing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-12 US claimed
US-20140187822-A1 METHOD FOR PRODUCING 2-CHLOROMETHYLBENZALDEHYDE, 2-CHLOROMETHYLBENZALDEHYDE-CONTAINING COMPOSITION, AND METHOD FOR STORING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 US claimed
EP-2727901-A1 METHOD FOR PRODUCING 2-CHLOROMETHYLBENZALDEHYDE, 2-CHLOROMETHYLBENZALDEHYDE-CONTAINING COMPOSITION, AND METHOD FOR STORING SAME Sumitomo Chemical Company Limited (JP) 2014-05-07 EP claimed
CN-103649034-A Method for producing 2-chloromethylbenzaldehyde, composition containing 2-chloromethylbenzaldehyde, and method for storing same SUMITOMO CHEMICAL CO 2014-03-19 CN claimed
EP-2058294-B1 METHOD FOR PRODUCING 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER SUMITOMO CHEMICAL CO (JP) 2013-01-02 EP claimed
US-20110288315-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND DAISO CO., LTD. (JP) 2011-11-24 US claimed
EP-2325178-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND DAISO CO., LTD. (JP) 2011-05-25 EP claimed
EP-0874807-B1 PROCESS FOR THE PREPARATION OF METHOXYMINOPHENYLGLYOXYLIC ACID DERIVATIVES BAYER AG (DE) 2002-02-20 EP claimed
CN-114605953-B Polyurethane sealant 北京东方雨虹防水技术股份有限公司 2024-04-23 CN disclosed
CN-114605604-B Curing agent with ionic liquid structure, preparation method and application 北京东方雨虹防水技术股份有限公司 2024-03-22 CN disclosed
CN-111954525-B Prodrugs of fused bicyclic C5aR antagonists 凯莫森特里克斯股份有限公司 2023-12-26 CN disclosed
WO-2023109387-A1 COUPLING OF SULFYDRYL-CONTAINING PEPTIDE AND FLUOROPORPHYRIN AS BIOLOGICAL PROBE 化学与精细化工广东省实验室 2023-06-22 WO disclosed
EP-0173172-A2 3-Pyridyl compounds and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-05 EP disclosed
EP-0169408-A1 Imidazolyl compounds, process for their preparation and their use as drugs HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-29 EP disclosed
US-4125552-A FROM A HALIDE, AMMONIA, HYDROCARBYLAMINE, HYDROGEN SULFIDE AND SULFUR DOW CORNING CORPORATION (US) 1978-11-14 US disclosed
US-4082790-A ORGANIC HALIDE, HYDROGEN SULFIDE, AMMONIA OR AMINE, POLAR SOLVENT DOW CORNING CORPORATION (US) 1978-04-04 US disclosed
US-4059447-A Photographic material containing oxazolinone-2 couplers AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288315-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND CYP51A1, KMO, TALDO1 LMNA 2146/4885KMT2A 346/4885MEN1 2011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.