Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150666 | 0.82 | MEN1 (0.41) | KMT2AMEN1TDP1LMNATHRB | |
| SCHEMBL31733135 | 0.82 | MEN1 (0.41) | KMT2AMEN1TDP1LMNATHRB | |
| SCHEMBL981676 | 0.79 | LMNA (0.55) | KMT2AMEN1TDP1LMNATHRB | |
| SCHEMBL30500760 | 0.79 | ALDH1A1 (0.45) | KMT2ATHRBALDH1A1HPGDTSHR | |
| SCHEMBL1538691 | 0.79 | ALDH1A1 (0.45) | KMT2ATHRBALDH1A1HPGDTSHR | |
| SCHEMBL10628208 | 0.78 | CYP1A2 (0.44) | KMT2AMEN1TDP1LMNATHRB | |
| SCHEMBL1350340 | 0.77 | LMNA (0.55) | KMT2AMEN1TDP1LMNATHRB | |
| SCHEMBL4944634 | 0.77 | THRB (0.52) | KMT2AMEN1TDP1LMNATHRB | |
| SCHEMBL3901145 | 0.77 | ERN1 (0.39) | KMT2AMEN1TDP1LMNATHRB | |
| SCHEMBL28025758 | 0.76 | MEN1 (0.42) | KMT2AMEN1TDP1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011918-A | Siloxane Derivatives Are Useful In Glass Fiber Sizing Compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4929670-A | GLASS SIZING COMPOSITIONS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4839449-A | SIZING COMPOSITION FOR GLASS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |