Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 8/20 | 0.43 |
| ▸ | CRY1 | Q16526 | 8/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 8/20 | 0.43 |
| ▸ | CMA1 | P23946 | 6/20 | 0.42 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508284 | 0.91 | PER2 (0.48) | PER2CRY1CRY2CMA1PFKFB4 | |
| SCHEMBL13508342 | 0.87 | CMA1 (0.46) | CMA1PFKFB4HTR6 | |
| SCHEMBL13508294 | 0.87 | CMA1 (0.46) | CMA1PFKFB4HTR6 | |
| SCHEMBL13508384 | 0.86 | LMNA (0.38) | PER2CRY1CRY2CMA1PFKFB4 | |
| SCHEMBL14338976 | 0.84 | PER2 (0.40) | PER2CMA1MEN1KMT2A | |
| SCHEMBL13508397 | 0.84 | PER2 (0.40) | PER2CMA1MEN1KMT2A | |
| SCHEMBL13508387 | 0.83 | PER2 (0.32) | PER2CRY1CRY2CMA1HTR6 | |
| SCHEMBL3686285 | 0.81 | CMA1 (0.36) | PER2CRY1CRY2CMA1PFKFB4 | |
| SCHEMBL5173377 | 0.81 | CMA1 (0.36) | PER2CRY1CRY2CMA1MEN1 | |
| SCHEMBL13509407 | 0.81 | CMA1 (0.35) | PER2CRY1CRY2CMA1PFKFB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |