Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 5/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508461 | 0.86 | MAOB (0.39) | HTR2BHRH1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL13508410 | 0.81 | MAOB (0.48) | KMT2AALDH1A1MEN1LMNACYP1A2 | |
| SCHEMBL13508434 | 0.81 | CYP19A1 (0.44) | HTR2BHRH1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL13508455 | 0.81 | MIF (0.54) | KMT2AALDH1A1MEN1LMNACYP1A2 | |
| SCHEMBL13508401 | 0.75 | CYP19A1 (0.55) | KMT2AALDH1A1MEN1LMNACYP1A2 | |
| SCHEMBL12998636 | 0.75 | MIF (0.55) | HTR2BHRH1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL4167023 | 0.74 | NR3C2 (0.46) | HTR2BHRH1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL4167020 | 0.74 | NR3C2 (0.46) | HTR2BHRH1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL4999010 | 0.73 | HTR2B (0.55) | HTR2BHRH1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL4173944 | 0.73 | HTR2B (0.55) | HTR2BHRH1KMT2AKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761962-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2010-02-03 | — | — | EP | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090159874-A1 | Organic electroluminescent devices | LEF1, NCS1, CRY1 | HTR2B 2687/4885HRH1 4047/4885KMT2A 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.