Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | M6PR | P20645 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19199441 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL7145634 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL7150678 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL23867729 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL13885812 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL23522673 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL7152243 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL23549931 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL22030605 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR | |
| SCHEMBL699606 | 1.00 | THRB (0.38) | THRBLMNAMEN1KMT2ATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679859-B2 | Method for functionalizing materials and devices comprising such materials | State of Oregon by and through the State Board of Higher Education on behalf of Porland State University (US) | 2014-03-25 | — | — | US | disclosed |
| US-20100028559-A1 | Method for functionalizing materials and devices comprising such materials | THE STATE OF OREGON ACTING BY AND THROUGH STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028559-A1 | Method for functionalizing materials and devices comprising such materials | ALDH1A2, LGALS3, LGALS3BP | THRB 4158/4885LMNA 879/4885MEN1 3122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.