Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193066 | 0.80 | CYP19A1 (0.53) | RAB9ASMN1; SMN2CYP19A1GSTO1MAPT | |
| SCHEMBL1194033 | 0.77 | RAB9A (0.80) | HTR2BRAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL13284002 | 0.76 | CYP19A1 (0.56) | RAB9ASMN1; SMN2CYP19A1GSTO1MAPT | |
| SCHEMBL2224538 | 0.75 | ALDH1A1 (0.55) | RAB9ASMN1; SMN2CYP19A1GSTO1MAPT | |
| SCHEMBL6686670 | 0.75 | TYR (0.66) | HTR2BRAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL14098391 | 0.75 | SMN1; SMN2 (0.61) | HTR2BRAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL13510369 | 0.74 | CYP19A1 (0.41) | HTR2BRAB9ASMN1; SMN2CYP19A1GSTO1 | |
| SCHEMBL1093303 | 0.74 | SMN1; SMN2 (0.60) | HTR2BRAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL6686667 | 0.72 | HTR2B (0.56) | HTR2BRAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL14098383 | 0.72 | RAB9A (0.54) | HTR2BRAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642324-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642324-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642216-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642216-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20090143222-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090143222-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090131619-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-20090131619-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-7387980-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX TECHNOLOGIES, INC. | 2008-06-17 | — | — | US | disclosed |
| US-7387980-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX TECHNOLOGIES, INC. | 2008-06-17 | — | — | US | disclosed |
| US-7256296-B2 | Heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX TECHNOLOGIES, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-7256296-B2 | Heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX TECHNOLOGIES, INC. (US) | 2007-08-14 | — | — | US | disclosed |