Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13511364 | 0.89 | MAOA (0.41) | PGRCHEK1CLK4CYP11B1CYP11B2 | |
| SCHEMBL13508064 | 0.87 | PGR (0.39) | PGRPARP10PARP11PDK2CHEK1 | |
| SCHEMBL13511400 | 0.82 | AKT1 (0.37) | CHEK1CLK4CYP11B1CYP11B2KMT2A | |
| SCHEMBL13511623 | 0.78 | KDM4E (0.32) | KMT2A | |
| SCHEMBL13511781 | 0.77 | AKT1 (0.34) | CHEK1CYP11B1CYP11B2KMT2A | |
| SCHEMBL13511795 | 0.76 | AKT1 (0.34) | CHEK1KMT2A | |
| SCHEMBL13507616 | 0.75 | RXRA (0.33) | CHEK1 | |
| SCHEMBL13511777 | 0.75 | KMT2A (0.33) | CHEK1KMT2A | |
| SCHEMBL13507715 | 0.74 | APP (0.33) | PDK2CHEK1 | |
| SCHEMBL13507589 | 0.74 | MEN1 (0.38) | CHEK1CLK4FYNDYRK1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145936-A2 | Fluorene and pyrene derivatives and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2010-01-20 | — | — | EP | disclosed |