Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251811 | 0.78 | CTSB (0.68) | CTSBCTSSCFTR | |
| SCHEMBL2835637 | 0.73 | CTSB (0.40) | CTSBCTSS | |
| SCHEMBL12658398 | 0.69 | CTSS (0.54) | CTSBCTSS | |
| SCHEMBL8241754 | 0.69 | DRD2 (0.35) | CTSB | |
| SCHEMBL2835019 | 0.69 | CTSB (0.54) | CTSBCTSS | |
| SCHEMBL8248577 | 0.68 | CTSS (0.49) | CTSBCTSS | |
| SCHEMBL2841189 | 0.67 | CTSB (0.49) | CTSBCTSSKDM4EALDH1A1 | |
| SCHEMBL8173753 | 0.67 | CTSS (0.67) | CTSBCTSS | |
| SCHEMBL2842529 | 0.67 | CTSS (0.54) | CTSBCTSS | |
| SCHEMBL3549335 | 0.66 | CTSB (0.50) | CTSBCTSSKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912981-B1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS | TIBOTEC PHARM LTD (IE) | 2010-01-20 | — | — | EP | disclosed |