Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13513364 | 0.94 | KCNJ6 (0.33) | F10SCN9AMAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL13513365 | 0.92 | L3MBTL1 (0.31) | SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL733848 | 0.92 | KMT2A (0.33) | F10SCN9AMAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL733847 | 0.92 | KMT2A (0.33) | F10SCN9AMAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL13513373 | 0.89 | GRIN2B (0.32) | SCN9AL3MBTL1 | |
| SCHEMBL732288 | 0.86 | KMT2A (0.33) | F10SCN9AMAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL732289 | 0.86 | KMT2A (0.33) | F10SCN9AMAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL13513379 | 0.86 | POLB (0.34) | SCN9AL3MBTL1GAANPSR1 | |
| SCHEMBL13513375 | 0.86 | XDH (0.34) | MAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL13513374 | 0.85 | SCN9A (0.34) | SCN9ASMN1; SMN2KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010006944-A1 | AMINOTETRAHYDROINDAZOLOACETIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-21 | — | — | WO | disclosed |