Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 9/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | SQOR | Q9Y6N5 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514590 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL13514637 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL13514245 | 0.82 | KDM4E (0.66) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22215646 | 0.74 | ALDH1A1 (0.82) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22215730 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22215651 | 0.73 | KDM4E (0.80) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL29442266 | 0.72 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22215728 | 0.72 | KDM4E (1.00) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL6252458 | 0.72 | ADORA2A (0.74) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22215727 | 0.71 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007756-A1 | PYRIDINE DERIVATIVE HAVING TTK INHIBITION ACTIVITY | 塩野義製薬株式会社 (JP) | 2010-01-21 | — | — | WO | disclosed |