Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 7/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | GLA | P06280 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | SQOR | Q9Y6N5 | 7/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514245 | 0.88 | KDM4E (0.66) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL6252458 | 0.82 | ADORA2A (0.74) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL13514249 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL13514590 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22208259 | 0.81 | SQOR (0.84) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL29442277 | 0.81 | SQOR (0.84) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL13514399 | 0.81 | SQOR (0.84) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL22215646 | 0.80 | ALDH1A1 (0.82) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22215730 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL22215727 | 0.79 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007756-A1 | PYRIDINE DERIVATIVE HAVING TTK INHIBITION ACTIVITY | 塩野義製薬株式会社 (JP) | 2010-01-21 | — | — | WO | disclosed |