SCHEMBL135148

SCHEMBL135148

CCCCCCCCC(Cl)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.59
FFAR1 O14842 2/20 0.59
MAPT P10636 1/20 0.57
LCK P06239 1/20 0.57
PPARD Q03181 1/20 0.57
ZDHHC20 Q5W0Z9 1/20 0.57
ZDHHC2 Q9UIJ5 1/20 0.57
ACE2 Q9BYF1 1/20 0.53
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48
FFAR4 Q5NUL3 1/20 0.48
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL737301 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8756278 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL17457273 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL11656847 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL4242789 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8115989 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1157874 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL9677063 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL9229604 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1263781 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108909-B Antibacterial rapidly water-soluble thermosetting system material and preparation method thereof 浙江工业大学 2024-10-29 CN claimed
CN-118620149-A Aggregate grading regulator for concrete and preparation method thereof 云南森博混凝土外加剂有限公司 2024-09-10 CN claimed
CN-115260127-A Preparation method of 5-pyrrolidinyl-2-phenylsulfonyl-2, 4-pentadienoic acid octyl ester 常州佳德医药科技有限公司 2022-11-01 CN claimed
CN-115108909-A Antibacterial rapidly water-soluble hot solid material and preparation method thereof 浙江工业大学 2022-09-27 CN claimed
JP-4808401-B2 2011-11-02 JP claimed
EP-1527038-B1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS LUCITE INT UK LTD (GB) 2010-03-17 EP claimed
CN-101535288-A Process for the preparation of duloxetine intermediate - (+) -N, N-dimethyl-3- (1-naphthyloxy) -3- (2-thienyl) propylamine TEVA PHARMA (IL) 2009-09-16 CN claimed
CN-101529047-A System for determining sealing in a wellbore SHELL INT RESEARCH (NL) 2009-09-09 CN claimed
US-7265240-B2 With CO in the presence of a source of hydroxyl groups (water or an alcohol) and a catalyst obtained by combining a Group VIII metal or a compound thereof and a bidentate phosphine, e.g., tri(dibenzylideneacetone)di-palladium LUCITE INTERNATIONAL UK LIMITED (GB) 2007-09-04 US claimed
US-20060122435-A1 Process for the carbonylation of ethylenically unsaturated compounds LUCITE INTERNATIONAL UK LIMITED (GB) 2006-06-08 US claimed
JP-2005535695-A 2005-11-24 JP claimed
EP-1527038-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS Lucite International UK Limited (GB) 2005-05-04 EP claimed
EP-1328190-B1 TEMPERATURE MEASURING BALLOON BOSTON SCIENT LTD (BB) 2004-12-29 EP claimed
WO-2004014834-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS LUCITE INTERNATIONAL UK LIMITED (GB) 2004-02-19 WO claimed
CN-115108909-B Antibacterial rapidly water-soluble thermosetting system material and preparation method thereof 浙江工业大学 2024-10-29 CN disclosed
CN-118620149-A Aggregate grading regulator for concrete and preparation method thereof 云南森博混凝土外加剂有限公司 2024-09-10 CN disclosed
CN-115724777-B Blue light absorption material, preparation method and application 南京工业大学 2024-07-02 CN disclosed
US-4130637-A BETAINES COLGATE-PALMOLIVE COMPANY (US) 1978-12-19 US disclosed
US-4051250-A OXAZOLE, THIAZOLE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-09-27 US disclosed
US-3933840-A ANTIPHLOGISTIC MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122435-A1 Process for the carbonylation of ethylenically unsaturated compounds CYC1, CYCS, COX5A GPR84 2564/4885FFAR1 2110/4885MAPT 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.