Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125558 | 0.76 | PIK3CD (0.35) | BACE1ALDH1A1HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL27859288 | 0.76 | BACE1 (0.38) | BACE1ALDH1A1KDM4ENT5EPTGS2 | |
| SCHEMBL2933943 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL15472863 | 0.73 | PLAU (0.57) | BACE1ALDH1A1HSP90AA1HSP90AB1KDM4E | |
| Hydrochloric Acid SCHEMBL28612763 | 0.71 | PLAU (0.55) | BACE1ALDH1A1HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL13515337 | 0.71 | PDE4B (0.37) | ALDH1A1KDM4ENT5EPTGS2MEN1 | |
| SCHEMBL30971512 | 0.71 | TRPV1 (0.40) | ALDH1A1HSP90AA1HSP90AB1KDM4EGAA | |
| SCHEMBL30503643 | 0.71 | LMNA (0.54) | BACE1ALDH1A1HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL3772488 | 0.71 | TRPV1 (0.40) | ALDH1A1HSP90AA1HSP90AB1KDM4EGAA | |
| SCHEMBL29685815 | 0.71 | TRPV4 (0.32) | NT5ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919903-B1 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-27 | — | — | EP | disclosed |