SCHEMBL13517364

SCHEMBL13517364

COC(=O)C1C2CC(C)C(C2)C1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.44
PTPN1 P18031 1/20 0.44
PPP1CC P36873 1/20 0.44
POLB P06746 1/20 0.39
CYP2C19 P33261 2/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC6A3 Q01959 1/20 0.35
PPP5C P53041 1/20 0.34
TP53 P04637 1/20 0.33
GRM2 Q14416 1/20 0.32
GRM3 Q14832 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14827597 0.95 PPM1B (0.43) PPM1BPTPN1PPP1CCPOLBCYP2C19
SCHEMBL14827595 0.95 PPM1B (0.43) PPM1BPTPN1PPP1CCPOLBCYP2C19
SCHEMBL13517143 0.95 PPM1B (0.43) PPM1BPTPN1PPP1CCPOLBCYP2C19
SCHEMBL13517141 0.90 CYP2C19 (0.38) PPM1BPTPN1PPP1CCCYP2C19CHRNB2
SCHEMBL16424387 0.87 PPP5C (0.35) PPM1BPTPN1PPP1CCPOLBPPP5C
SCHEMBL3277776 0.86 PPP5C (0.39) POLBALDH1A1KMT2APPP5CGRM2
SCHEMBL11149524 0.83 CYP2C19 (0.36) PPM1BPTPN1PPP1CCCYP2C19CHRNB2
SCHEMBL13517008 0.82 PPP5C (0.33) CHRNB2CHRNB4CHRNA3CHRNA4SLC6A3
SCHEMBL3694476 0.81 PPM1B (0.44) PPM1BPTPN1PPP1CCPOLBCYP2C19
SCHEMBL20928970 0.80 PPM1B (0.43) PPM1BPTPN1PPP1CCPOLBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308563-B2 Process for producing ethylene oligomers HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2019-06-04 US disclosed
EP-2524930-B1 PREPARATION METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION, AND CATALYST PREPARED THEREBY HANWHA TOTAL PETROCHEMICAL CO LTD (KR) 2018-09-12 EP disclosed
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-9045572-B2 Preparation method of solid catalyst for propylene polymerization and catalyst prepared thereby SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2015-06-02 US disclosed
EP-1550688-B1 ORGANOPOLYSILOXANE-MODIFIED POLYSACCHARIDE AND PROCESS FOR PRODUCING THE SAME DOW CORNING TORAY CO LTD (JP) 2014-03-19 EP disclosed
US-20140005345-A1 SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND A METHOD FOR PREPARATION OF POLYPROPYLENE HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2014-01-02 US disclosed
US-8394734-B2 Solid catalyst for propylene polymerization and a method for preparation of polypropylene using the same SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2013-03-12 US disclosed
US-20130017946-A1 PREPARATION METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND CATALYST PREPARED THEREBY SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2013-01-17 US disclosed
EP-2524930-A2 PREPARATION METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION, AND CATALYST PREPARED THEREBY Samsung Total Petrochemicals Co. Ltd. (KR) 2012-11-21 EP disclosed
US-20120277389-A1 SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND A METHOD FOR PREPARATION OF POLYPROPYLENE USING THE SAME SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2012-11-01 US disclosed
US-7199205-B2 Organopolysiloxane-modified polysaccharide and process for producing the same DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 2007-04-03 US disclosed
US-7199205-B2 Organopolysiloxane-modified polysaccharide and process for producing the same DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 2007-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308563-B2 Process for producing ethylene oligomers OXER1, HAO2, ORC3 PPM1B 4279/4885PTPN1 4333/4885PPP1CC 4764/4885
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HACL2, HAO2, MSMO1 PPM1B 4507/4885PTPN1 4589/4885PPP1CC 4861/4885
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS OXER1, HAO2, ORC3 PPM1B 4279/4885PTPN1 4333/4885PPP1CC 4764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.