SCHEMBL3277776

SCHEMBL3277776

CC1CC2CC1C(C(=O)O)C2C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPP5C P53041 1/20 0.39
POLB P06746 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
GRM2 Q14416 7/20 0.36
GRM3 Q14832 4/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
PKM P14618 1/20 0.34
GRM6 O15303 4/20 0.33
LMNA P02545 3/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.31
GRM5 P41594 4/20 0.31
GRM1 Q13255 2/20 0.31
GRM4 Q14833 2/20 0.31
ALDH1A1 P00352 1/20 0.31
APEX1 P27695 1/20 0.30
MAPK1 P28482 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16424387 0.88 PPP5C (0.35) PPP5CPOLBTDP1GRM2GRM3
SCHEMBL13517364 0.86 PPM1B (0.44) PPP5CPOLBGRM2GRM3KMT2A
SCHEMBL13517143 0.85 PPM1B (0.43) PPP5CPOLBKMT2AALDH1A1
SCHEMBL14827595 0.85 PPM1B (0.43) PPP5CPOLBKMT2AALDH1A1
SCHEMBL14827597 0.85 PPM1B (0.43) PPP5CPOLBKMT2AALDH1A1
SCHEMBL13170546 0.84 PPP5C (0.38) PPP5CPOLBTDP1GRM2GRM3
SCHEMBL13170547 0.84 PPP5C (0.38) PPP5CPOLBTDP1GRM2GRM3
SCHEMBL13170552 0.84 PPP5C (0.38) PPP5CPOLBTDP1GRM2GRM3
SCHEMBL11156035 0.84 PPP5C (0.38) PPP5CPOLBTDP1GRM2GRM3
SCHEMBL13170553 0.84 PPP5C (0.38) PPP5CPOLBTDP1GRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308563-B2 Process for producing ethylene oligomers HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2019-06-04 US disclosed
EP-2524930-B1 PREPARATION METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION, AND CATALYST PREPARED THEREBY HANWHA TOTAL PETROCHEMICAL CO LTD (KR) 2018-09-12 EP disclosed
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-9045572-B2 Preparation method of solid catalyst for propylene polymerization and catalyst prepared thereby SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2015-06-02 US disclosed
CN-103509142-A Solid catalyst for propylene polymerization and a method for preparation of polypropylene SAMSUNG TOTAL PETROCHEMICALS 2014-01-15 CN disclosed
US-20140005345-A1 SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND A METHOD FOR PREPARATION OF POLYPROPYLENE HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2014-01-02 US disclosed
EP-2644628-A2 SOLID CATALYST FOR THE POLYMERIZATION OF PROPYLENE, AND METHOD FOR PREPARING SAME Samsung Total Petrochemicals Co. Ltd. (KR) 2013-10-02 EP disclosed
US-20130237406-A1 SOLID CATALYST FOR THE POLYMERIZATION OF PROPYLENE, AND METHOD FOR PREPARING SAME SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2013-09-12 US disclosed
US-8394734-B2 Solid catalyst for propylene polymerization and a method for preparation of polypropylene using the same SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2013-03-12 US disclosed
US-20130017946-A1 PREPARATION METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND CATALYST PREPARED THEREBY SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2013-01-17 US disclosed
EP-2524930-A2 PREPARATION METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION, AND CATALYST PREPARED THEREBY Samsung Total Petrochemicals Co. Ltd. (KR) 2012-11-21 EP disclosed
US-20120277389-A1 SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND A METHOD FOR PREPARATION OF POLYPROPYLENE USING THE SAME SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2012-11-01 US disclosed
US-7700802-B2 by utilizing the difference in solubility between a neutralized salt of the endo isomer and a neutral salt of the exo isomer of a dicarboxylic acid having a norbornene or norbornane structure; mixing the above endo and exo mixture with NaOH and a solvent, filtering to separate liquid and solid phase HITACHI CHEMICAL CO., LTD. (JP) 2010-04-20 US disclosed
US-20070142668-A1 Method of separating stereoisomers of dicarboxylic acid having norbornene or norbornane structure, or derivative thereof HITACHI CHEMICAL CO., LTD. (JP) 2007-06-21 US disclosed
EP-1669342-A1 METHOD OF SEPARATING STEREOISOMERS OF NORBORNENE, DICARBOXYLIC ACID HAVING NORBORNANE STRUCTURE, OR DERIVATIVE THEREOF Hitachi Chemical Co., Ltd. (JP) 2006-06-14 EP disclosed
EP-0776924-A2 Polyimide composition and method for producing prepreg and paint using the same MITSUBISHI JUKOGYO KABUSHIKI KAISHA (JP) 1997-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308563-B2 Process for producing ethylene oligomers OXER1, HAO2, ORC3 PPP5C 4851/4885POLB 1375/4885TDP1 1797/4885
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HACL2, HAO2, MSMO1 PPP5C 4880/4885POLB 1591/4885TDP1 2113/4885
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS OXER1, HAO2, ORC3 PPP5C 4851/4885POLB 1375/4885TDP1 1797/4885
US-20070142668-A1 Method of separating stereoisomers of dicarboxylic acid having norbornene or norbornane structure, or derivative thereof EXOC1, RER1, PRMT8 PPP5C 4740/4885POLB 2359/4885TDP1 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.