Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | SHBG | P04278 | 4/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.70 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13965592 | 0.89 | LMNA (0.67) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL572198 | 0.89 | LMNA (0.67) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL3931615 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL18261234 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL14523053 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL23456341 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL24287585 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL13558389 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL265609 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| Hydroxyprogesterone SCHEMBL14546356 | 0.82 | LMNA (1.00) | LMNASHBGCYP2C19NR3C1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190038637-A1 | Use of Hydroxyprogesterone Derivatives for Enhanced Health and Physical Performance II | MARCHEWITZ ERIC (US) | 2019-02-07 | — | — | US | disclosed |
| US-20120277201-A1 | Use of hydroxyprogesterone derivatives for enhancing health and physical performance | MARCHEWITZ ERIC D (US) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277201-A1 | Use of hydroxyprogesterone derivatives for enhancing health and physical performance | HSD17B11, HSD17B1, CYP19A1 | LMNA 2630/4885SHBG 17/4885CYP2C19 49/4885 |
| US-20190038637-A1 | Use of Hydroxyprogesterone Derivatives for Enhanced Health and Physical Performance II | HSD17B11, HSD17B2, HSD17B1 | LMNA 2511/4885SHBG 17/4885CYP2C19 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.