Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.67 |
| ▸ | SHBG | P04278 | 5/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13965592 | 1.00 | LMNA (0.67) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL6693993 | 0.89 | LMNA (0.53) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL6693991 | 0.89 | LMNA (0.53) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL13518429 | 0.89 | LMNA (0.70) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL295690 | 0.88 | LMNA (0.51) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL9128581 | 0.86 | SHBG (0.65) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL9128571 | 0.86 | SHBG (0.65) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL11205039 | 0.86 | NR3C1 (0.60) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL15079253 | 0.86 | LMNA (0.49) | LMNASHBGNR3C1CYP2C19MEN1 | |
| SCHEMBL10444770 | 0.86 | LMNA (0.49) | LMNASHBGNR3C1CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113583074-A | Novel preparation method of 6-methyl-17 alpha-hydroxyprogesterone and precursor thereof | 佳尔科生物科技南通有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| CN-113583074-A | Novel preparation method of 6-methyl-17 alpha-hydroxyprogesterone and precursor thereof | 佳尔科生物科技南通有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113583074-A | Novel preparation method of 6-methyl-17 alpha-hydroxyprogesterone and precursor thereof | 佳尔科生物科技南通有限公司 | 2021-11-02 | — | — | CN | disclosed |
| US-20140234271-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2014-08-21 | — | — | US | disclosed |
| US-8748177-B2 | Compositions for proliferation of cells and related methods | THE HOSPITAL FOR SICK CHILDREN (CA) | 2014-06-10 | — | — | US | disclosed |
| EP-2598150-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | The Hospital For Sick Children (CA) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018643-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2012-02-09 | — | — | WO | disclosed |
| US-20110301105-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2011-12-08 | — | — | US | disclosed |
| WO-2010039679-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2010-04-08 | — | — | WO | disclosed |
| CN-1178699-C | Pharmaceutical Compsns. contg. compounds with activity for enhancement of absorption of active ingredients | — | 2004-12-08 | — | — | CN | disclosed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | disclosed |
| EP-0179496-A1 | 16-Sulfinylmethyl-steroids, their preparation and use | THE UPJOHN COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4443377-A | Isomerization-acylation process | THE UPJOHN COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| EP-0104054-A2 | 16-methylene-steroids and their preparation | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |
| EP-0034115-B1 | PROCESS FOR THE PREPARATION OF 6-METHYLENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-08 | — | — | EP | disclosed |
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |
| EP-0034115-A2 | Process for the preparation of 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234271-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | MKI67, KRT18, PROX1 | LMNA 2509/4885SHBG 1806/4885NR3C1 3193/4885 |
| US-20110301105-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | MKI67, KRT18, PROX1 | LMNA 2509/4885SHBG 1806/4885NR3C1 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.