Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13519664 | 0.85 | ALDH1A1 (0.33) | ALDH1A1HRH2HRH1KMT2ASMN1; SMN2 | |
| SCHEMBL13520228 | 0.77 | CHRM3 (0.43) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13520211 | 0.74 | HRH2 (0.40) | ALDH1A1HRH2HRH1MEN1KMT2A | |
| SCHEMBL10856497 | 0.71 | GAA (0.52) | ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9326877 | 0.71 | GAA (0.49) | ALDH1A1HRH2HRH1MEN1KMT2A | |
| SCHEMBL16363479 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HRH2HRH1MEN1KMT2A | |
| SCHEMBL22882677 | 0.69 | MGAM (0.43) | ALDH1A1MEN1KMT2AL3MBTL1SLC29A1 | |
| SCHEMBL10174987 | 0.67 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AL3MBTL1SLC29A1 | |
| SCHEMBL17401259 | 0.67 | DGKA (0.67) | ALDH1A1HRH2HRH1MEN1KMT2A | |
| SCHEMBL11628693 | 0.67 | DGKA (0.67) | ALDH1A1HRH2HRH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642245-B2 | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif | OSCIENT PHARMACEUTICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070142268-A1 | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif | OSCIENT PHARMACEUTICALS CORPORATION (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142268-A1 | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif | AADAC, MRPL21, HDAC6 | ALDH1A1 1422/4885HRH2 1172/4885HRH1 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.