Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130633 | 0.77 | PNMT (0.55) | PLG | |
| SCHEMBL14997332 | 0.70 | CYP2D6 (0.37) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10967469 | 0.69 | MEN1 (0.39) | TAAR1HTR2A | |
| SCHEMBL10132275 | 0.69 | POLB (0.58) | PLGHTR2A | |
| SCHEMBL20828166 | 0.69 | POLB (0.58) | PLGHTR2A | |
| SCHEMBL23222206 | 0.68 | PLG (0.48) | PLGTAAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL22453306 | 0.66 | TRPA1 (0.45) | PLGTAAR1IDO1AGXTALDH1A1 | |
| SCHEMBL22453507 | 0.66 | TRPA1 (0.45) | PLGTAAR1IDO1AGXTALDH1A1 | |
| SCHEMBL3129776 | 0.66 | PNMT (0.47) | HTR2A | |
| SCHEMBL22445110 | 0.65 | PLG (0.45) | PLGTAAR1IDO1AGXTCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2143714-A1 | TETRAHYDROISOQUINOLINE COMPOUND | Kowa Company, Ltd. (JP) | 2010-01-13 | — | — | EP | disclosed |