Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13321972 | 0.86 | TTR (0.40) | LMNAMAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL13819211 | 0.82 | NPC1 (0.39) | LMNAMAPK1SMN1; SMN2MCL1NPC1 | |
| SCHEMBL13321956 | 0.81 | ALDH1A1 (0.41) | LMNAMAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL13106020 | 0.80 | PNLIP (0.40) | LMNASMN1; SMN2KMT2AL3MBTL1PTGDR2 | |
| SCHEMBL13522285 | 0.79 | NPC1 (0.37) | LMNAMAPK1SMN1; SMN2PPARGPPARD | |
| SCHEMBL4891781 | 0.79 | TTR (0.44) | ESR1ESR2 | |
| SCHEMBL14401996 | 0.78 | FGFR2 (0.36) | SMN1; SMN2ALDH1A1PPARGPPARAL3MBTL1 | |
| SCHEMBL13106024 | 0.77 | PDK2 (0.38) | MAPK1L3MBTL1PTGDR2CYP2C9 | |
| SCHEMBL13106029 | 0.76 | KMT2A (0.44) | LMNASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL13321966 | 0.75 | ESR1 (0.44) | LMNAMAPK1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645534-B2 | Membrane electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. (JP) | 2010-01-12 | — | — | US | disclosed |