Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15856301 | 0.81 | ROCK1 (0.46) | ROCK1HSP90AA1GPR3PRNPRXFP1 | |
| SCHEMBL13477893 | 0.79 | ROCK1 (0.48) | ROCK1GPR3PRNPRXFP1ALDH1A1 | |
| SCHEMBL4262796 | 0.77 | ROCK1 (0.49) | ROCK1GPR3PRNPRXFP1ALOX5 | |
| SCHEMBL16482779 | 0.70 | ROCK1 (0.46) | ROCK1HSP90AA1GPR3PRNPRXFP1 | |
| 2-Phenylphenol SCHEMBL8067945 | 0.70 | HPGD (0.65) | GPR3ALOX5L3MBTL1ALDH1A1MAPT | |
| SCHEMBL356324 | 0.69 | ALOX5 (0.64) | GPR3ALOX5L3MBTL1ALDH1A1MAPT | |
| SCHEMBL13477894 | 0.69 | ROCK1 (0.46) | ROCK1GPR3L3MBTL1ALDH1A1MAPT | |
| SCHEMBL144440 | 0.68 | GPR3 (0.55) | ROCK1GPR3PRNPRXFP1ALDH1A1 | |
| SCHEMBL2338956 | 0.67 | GPR3 (0.54) | GPR3ALOX5L3MBTL1ALDH1A1MAPT | |
| SCHEMBL14178295 | 0.67 | ROCK1 (0.40) | ROCK1GPR3PRNPRXFP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |