SCHEMBL144440

SCHEMBL144440

Cc1sc2ccccc2c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.55
ALDH1A1 P00352 4/20 0.47
PRNP P04156 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
ROCK1 Q13464 1/20 0.42
CYP1A2 P05177 3/20 0.41
CYP2D6 P10635 2/20 0.41
CYP1A1 P04798 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
HTR2A P28223 1/20 0.41
CYP2C19 P33261 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
HSD17B10 Q99714 1/20 0.41
FTO Q9C0B1 1/20 0.41
MAPT P10636 3/20 0.40
HSD11B1 P28845 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28459123 0.98 GPR3 (0.52) GPR3ALDH1A1PRNPRXFP1ROCK1
SCHEMBL10330425 0.82 ALDH1A1 (0.50) GPR3ALDH1A1PRNPRXFP1CYP1A2
SCHEMBL21788492 0.78 GPR3 (0.47) GPR3ALDH1A1ROCK1CYP1A2MAPT
SCHEMBL9310785 0.76 GPR3 (0.50) GPR3ALDH1A1PRNPRXFP1CYP1A2
SCHEMBL5295130 0.76 GPR3 (0.50) GPR3ALDH1A1PRNPRXFP1ROCK1
SCHEMBL16900681 0.76 GPR3 (0.50) GPR3ALDH1A1PRNPRXFP1ROCK1
SCHEMBL13511901 0.76 GPR3 (0.50) GPR3ALDH1A1PRNPRXFP1CYP1A2
SCHEMBL1121831 0.76 GPR3 (0.50) GPR3ALDH1A1PRNPRXFP1ROCK1
SCHEMBL718497 0.76 GPR3 (0.50) GPR3ALDH1A1CYP1A2CYP2D6CYP1A1
SCHEMBL9407733 0.76 GPR3 (0.50) GPR3ALDH1A1PRNPRXFP1ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094306-A Chiral heterojunction-based light-emitting synaptic device and preparation method thereof 2026-05-26 CN claimed
US-20250206686-A1 METHODS TO SEPARATE MOLECULES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2025-06-26 US claimed
CN-118921993-A Flexible organic transistor array for ammonia gas detection and preparation method thereof 复旦大学 2024-11-08 CN claimed
US-10889601-B2 Separations using boron containing hydrocarbon sponges UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2021-01-12 US claimed
US-20200255454-A1 SEPARATIONS USING BORON CONTAINING HYDROCARBON SPONGES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2020-08-13 US claimed
CN-106866616-A A kind of method for preparing thiophene-type sulfide 武汉工程大学 2017-06-20 CN claimed
US-9315740-B2 Methods of separating mixtures of miscible fluids ORBITAL ATK, INC. (US) 2016-04-19 US claimed
US-20140166539-A1 METHOD OF LIQUID FUEL DESULFURIZATION ALLIANT TECHSYSTEMS, INC. (US) 2014-06-19 US claimed
CN-102989493-A Preparation method of heavy oil hydrotreating composite catalyst PETROCHINA CO LTD 2013-03-27 CN claimed
US-8057577-B2 Desulfurizer for fuel gas for fuel cell and desulfurization method using the same SAMSUNG SDI CO., LTD. (KR) 2011-11-15 US claimed
CN-101024138-B Desulfurizer for fuel gas for fuel cell and desulfurization method using the same SAMSUNG SDI CO LTD 2010-05-19 CN claimed
CN-101024138-A Desulfurizer for fuel gas for fuel cell and desulfurization method using the same SAMSUNG SDI CO LTD (KR) 2007-08-29 CN claimed
US-20070196258-A1 Desulfurizer for fuel gas for fuel cell and desulfurization method using the same SAMSUNG SDI CO., LTD (KR) 2007-08-23 US claimed
WO-2007001335-A2 RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. (US) 2007-01-04 WO claimed
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity VICURON PHARMACEUTICALS INC. (US) 2006-09-21 US claimed
US-4463096-A Petroleum source rock identification PHILLIPS PETROLEUM COMPANY (US) 1984-07-31 US claimed
CN-122094306-A Chiral heterojunction-based light-emitting synaptic device and preparation method thereof 2026-05-26 CN disclosed
US-12583870-B2 Azaheteroaryl compound and application thereof SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) 2026-03-24 US disclosed
EP-0653477-A2 Desulfurization and denitration of light oil by extraction GENERAL SEKIYU KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
EP-0538738-A2 Desulfurization and Decolourizing of light oil by extraction GENERAL SEKIYU KABUSHIKI KAISHA (JP) 1993-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583870-B2 Azaheteroaryl compound and application thereof NR3C1, EED, EZH2 GPR3 1653/4885ALDH1A1 1634/4885PRNP 3108/4885
US-10889601-B2 Separations using boron containing hydrocarbon sponges BCL6B, CXCR2, CXCR1 GPR3 1533/4885ALDH1A1 2606/4885PRNP 4778/4885
US-20250206686-A1 METHODS TO SEPARATE MOLECULES BTF3, TPR, TBCB GPR3 886/4885ALDH1A1 4190/4885PRNP 816/4885
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity CLSPN, LMAN2, RPN2 GPR3 2472/4885ALDH1A1 2972/4885PRNP 2865/4885
US-20200255454-A1 SEPARATIONS USING BORON CONTAINING HYDROCARBON SPONGES BCL6B, CXCR2, CXCR1 GPR3 1533/4885ALDH1A1 2606/4885PRNP 4778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.