Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.52 |
| ▸ | NPC1 | O15118 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RUNX1 | Q01196 | 3/20 | 0.42 |
| ▸ | CBFB | Q13951 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522997 | 0.83 | GAA (0.50) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL983700 | 0.81 | MAPT (0.61) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL13523006 | 0.80 | ILK (0.42) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL2906176 | 0.80 | MAPT (0.59) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL3302516 | 0.78 | MAPT (0.67) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29478087 | 0.78 | MAPT (0.67) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7258252 | 0.78 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11896552 | 0.74 | GCK (0.50) | SMN1; SMN2ALDH1A1NR4A2TDP1TSHR | |
| SCHEMBL13053004 | 0.72 | PDK1 (0.55) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL13998719 | 0.72 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |