Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 5/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309721 | 0.86 | GCK (0.47) | GCKCYP1A1CYP1A2CYP1B1HSP90AA1 | |
| SCHEMBL457582 | 0.82 | HSP90AA1 (0.43) | GCKHSP90AA1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2029417 | 0.82 | FBP1 (0.45) | GCKIDO1CYP1A1CYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL4612966 | 0.81 | HSP90AA1 (0.42) | GCKHSP90AA1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6129331 | 0.79 | CYP1A2 (0.42) | GCKCYP1A1CYP1A2CYP1B1ALDH1A1 | |
| SCHEMBL996582 | 0.79 | F2RL1 (0.49) | CYP1A1CYP1A2CYP1B1HSP90AA1TSHR | |
| SCHEMBL999144 | 0.79 | SRC (0.42) | HSP90AA1TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL4613518 | 0.79 | ADRB2 (0.40) | GCKCYP1A1CYP1A2CYP1B1HSP90AA1 | |
| SCHEMBL8859981 | 0.79 | FBP1 (0.49) | CYP1A1CYP1A2CYP1B1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10517968 | 0.78 | F2RL1 (0.48) | CYP1A1CYP1A2CYP1B1HSP90AA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668186-B1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK BIOPHARMACEUTICALS CO LTD (KR) | 2017-05-03 | — | — | EP | disclosed |
| US-8716309-B2 | Pharmaceutical composition comprising pyridone derivatives | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-05-06 | — | — | US | disclosed |
| EP-2668186-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK Biopharmaceuticals Co., Ltd. (KR) | 2013-12-04 | — | — | EP | disclosed |
| US-20130317059-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2013-11-28 | — | — | US | disclosed |
| WO-2012102580-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130317059-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | PLPBP, PDXK, PIR | GCK 59/4885IDO1 1203/4885CYP1A1 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.