Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | IDE | P14735 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HLCS | P50747 | 6/20 | 0.64 |
| ▸ | CA12 | O43570 | 6/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.60 |
| ▸ | CA2 | P00918 | 6/20 | 0.60 |
| ▸ | CA9 | Q16790 | 6/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899174 | 1.00 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL4757050 | 1.00 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13274150 | 1.00 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5903676 | 1.00 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8165184 | 1.00 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10171679 | 1.00 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL12238074 | 1.00 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL24653263 | 0.99 | TDP1 (0.71) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL15130533 | 0.96 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL26902859 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240961-A1 | AFFINITY TAG LABELED NUCLEOSIDES AND USES | COMPLETE GENOMICS, INC. (US) | 2017-08-24 | — | — | US | disclosed |
| US-9045516-B2 | Synthetic ligands for the differentiation of closely related toxins and pathogens | UNIVERSITY OF CINCINNATI | 2015-06-02 | — | — | US | disclosed |
| US-8298513-B2 | Hexatriene-β-carbonyl compound | OSAKA UNIVERSITY (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20100008857-A1 | NOVEL HEXATRIENE-BETA-CARBONYL COMPOUND | OSAKA UNIVERSITY (JP) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100008857-A1 | NOVEL HEXATRIENE-BETA-CARBONYL COMPOUND | CBR1, CBR3, DCXR | TDP1 4770/4885MEN1 4487/4885ABL1 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.