Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525222 | 0.84 | PABPC1 (0.36) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL13525223 | 0.77 | KDM4E (0.36) | PABPC1MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL13525210 | 0.76 | PABPC1 (0.49) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL11309468 | 0.75 | PABPC1 (0.67) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL11316017 | 0.75 | PABPC1 (0.61) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL11305866 | 0.73 | PABPC1 (0.49) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL11790187 | 0.72 | PABPC1 (0.50) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL20280495 | 0.71 | PABPC1 (0.69) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL12428488 | 0.71 | CA2 (0.38) | PABPC1MEN1KMT2ACA12CA2 | |
| SCHEMBL29423636 | 0.71 | PABPC1 (0.69) | PABPC1MEN1KMT2ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645304-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-12 | — | — | US | disclosed |
| US-7645304-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-12 | — | — | US | disclosed |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | KRT18, IK, KLK5 | PABPC1 3727/4885MEN1 1750/4885KMT2A 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.