SCHEMBL13525237

SCHEMBL13525237

CC(=O)NC1=CC(=O)C(C)=CC1=Nc1ccc(N(C)C)c(Cl)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PABPC1 P11940 1/20 0.32
▸ FSCN1 Q16658 1/20 0.32
▸ S100A4 P26447 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11321392 0.88 PABPC1 (0.34) PABPC1FSCN1
SCHEMBL13525218 0.86 CYP1A2 (0.36) —
SCHEMBL13525227 0.82 HSP90AA1 (0.32) PABPC1FSCN1
SCHEMBL13525226 0.81 PGK1 (0.37) —
SCHEMBL13525211 0.77 HTT (0.33) S100A4
SCHEMBL13525234 0.74 ESR1 (0.33) —
SCHEMBL1435815 0.74 KDM4E (0.33) —
SCHEMBL1435819 0.74 KDM4E (0.33) —
SCHEMBL13525232 0.73 MAPT (0.37) PABPC1S100A4
SCHEMBL11309470 0.72 PABPC1 (0.38) PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645304-B2 Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation L'OREAL S.A. (FR) 2010-01-12 — — US disclosed
US-7645304-B2 Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation L'OREAL S.A. (FR) 2010-01-12 — — US disclosed
US-20080120792-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation L'OREAL S.A. (FR) 2008-05-29 — — US disclosed
US-20080120792-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation L'OREAL S.A. (FR) 2008-05-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080120792-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation KRT18, IK, KLK5 PABPC1 3727/4885FSCN1 732/4885S100A4 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback