Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435819 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1GLAGAACA1 | |
| SCHEMBL11256805 | 0.87 | KDM4E (0.33) | KDM4EALDH1A1GLAGAACA1 | |
| SCHEMBL13525233 | 0.85 | CYP1A2 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL13525226 | 0.78 | PGK1 (0.37) | KDM4EALDH1A1GAACA1CA2 | |
| SCHEMBL13525211 | 0.78 | HTT (0.33) | ALDH1A1 | |
| SCHEMBL13525237 | 0.74 | PABPC1 (0.32) | — | |
| SCHEMBL11410525 | 0.74 | ABCB11 (0.31) | ALDH1A1 | |
| SCHEMBL13525239 | 0.73 | CA1 (0.38) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL13525218 | 0.70 | CYP1A2 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL7593877 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2355904-B1 | HAIR CONDITIONING COMPOSITION COMPRISING CATIONIC SURFACTANT SYSTEM AND DIRECT DYE | PROCTER & GAMBLE (US) | 2017-01-04 | — | — | EP | disclosed |
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-9289630-B2 | Hair conditioning composition comprising cationic surfactant system, direct dye, and nonionic thickener | THE PROCTER & GAMBLE COMPANY (US) | 2016-03-22 | — | — | US | disclosed |
| US-9248086-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9248086-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9161898-B2 | Compositions for colouring keratin fibres | HENKEL AG & CO. KGAA (DE) | 2015-10-20 | — | — | US | disclosed |
| US-9126057-B2 | Hair conditioning composition comprising cationic surfactant system and direct dye | THE PROCTER & GAMBLE COMPANY (US) | 2015-09-08 | — | — | US | disclosed |
| WO-2006107595-A1 | REDUCTIVE COLORANT FOR KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |
| EP-1707188-A1 | Reductive colouring system for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1707187-A1 | Reductive colorant for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2006081246-A2 | USE OF CATIONIC AZACYANINE DYES FOR COLORING KERATIN FIBERS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-03 | — | — | WO | disclosed |
| US-20060140892-A1 | Method for generation of memory effects on hair | LENDLEIN ANDREAS | 2006-06-29 | — | — | US | disclosed |
| US-20060088494-A1 | Method of treating hair with form memory polymers | MNEMOSCIENCE GMBH (DE) | 2006-04-27 | — | — | US | disclosed |
| US-20050226838-A1 | Hair treatment compositions containing N-hydroxy-alkyl-O-benzyl chitosans and methods of using same | WELLA AG (DE) | 2005-10-13 | — | — | US | disclosed |
| US-20040228809-A1 | A container is filled with a mixture of a cationic cellulose derivative (Polyquaternium), chitosans, one acid for neutralizing, a solvent, pumping with or without a propellant; film-forming nonionic polymer improves hair fixing properties, nondepositing; hair dyes | Wella GmbH (DE) | 2004-11-18 | — | — | US | disclosed |
| US-20040037786-A1 | Aerosol foam product for hair treatment | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | disclosed |
| US-20030215479-A1 | Process for manufacture of hair or skin cosmetic products using apparatuses with microstructured units | WELLA AKTIENGESELLSCHART (DE) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050226838-A1 | Hair treatment compositions containing N-hydroxy-alkyl-O-benzyl chitosans and methods of using same | CYP8B1, HAAO, TYR | KDM4E 669/4885ALDH1A1 1251/4885GLA 401/4885 |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KDM4E 2691/4885ALDH1A1 192/4885GLA 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.