Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10876362 | 0.77 | ALDH1A1 (0.70) | ALDH1A1MAOABCHECES1CYP1A2 | |
| SCHEMBL7611787 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAOABCHECES1CYP1A2 | |
| Fluorene SCHEMBL30341649 | 0.70 | MAOA (0.58) | ALDH1A1MAOABCHECES1CYP1A2 | |
| Fluorene SCHEMBL27708363 | 0.70 | MAOA (0.58) | ALDH1A1MAOABCHECES1CYP1A2 | |
| Fluorene SCHEMBL28233312 | 0.69 | MAOA (0.56) | ALDH1A1MAOABCHECES1CYP1A2 | |
| Fluorene SCHEMBL11677474 | 0.69 | MAOA (0.58) | ALDH1A1MAOABCHECES1CYP1A2 | |
| Fluorene SCHEMBL2131210 | 0.69 | SRD5A2 (0.60) | ALDH1A1MAOABCHECES1CYP1A2 | |
| SCHEMBL23790313 | 0.68 | ALDH1A1 (0.73) | ALDH1A1MAOABCHECES1CYP1A2 | |
| Fluorene SCHEMBL28263838 | 0.68 | MAOA (0.61) | ALDH1A1MAOABCHECES1CYP1A2 | |
| Fluorene SCHEMBL28751075 | 0.67 | SRD5A2 (0.58) | ALDH1A1MAOABCHECES1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016465-A1 | Composite Material Comprising A Water-Or Acid-Releasing Agent | DENTOFIT A/S (DK) | 2010-01-21 | — | — | US | disclosed |
| US-20100016465-A1 | Composite Material Comprising A Water-Or Acid-Releasing Agent | DENTOFIT A/S (DK) | 2010-01-21 | — | — | US | disclosed |
| WO-2007104312-A2 | COMPOSITE MATERIAL, IN PARTICULAR A DENTAL FILLING MATERIAL | DENTOFIT A/S (DK) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016465-A1 | Composite Material Comprising A Water-Or Acid-Releasing Agent | PLA2G2C, SMARCA1, VMA21 | ALDH1A1 1006/4885MAOA 401/4885BCHE 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.