SCHEMBL1353048

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1353976	0.86	HDAC8 (0.77)	HDAC8MEN1KMT2ARAB9ANPC1
	SCHEMBL24118881	0.82	STAT3 (0.75)	HDAC8GRM5MEN1KMT2ARAB9A
	SCHEMBL1352779	0.82	HDAC8 (0.61)	HDAC8MEN1KMT2ARAB9ANPC1
	SCHEMBL1353005	0.82	RXFP1 (0.64)	HDAC8MAPT
	SCHEMBL1351867	0.82	HDAC8 (0.57)	HDAC8MEN1KMT2ARAB9ANPC1
	SCHEMBL24118801	0.82	GRM5 (0.83)	HDAC8GRM5MEN1KMT2ARAB9A
	SCHEMBL1353390	0.81	HDAC8 (0.62)	HDAC8MEN1KMT2ARAB9ANPC1
	SCHEMBL1353484	0.81	NPC1 (0.71)	HDAC8MEN1KMT2ARAB9ANPC1
	SCHEMBL1353382	0.81	KCNMA1 (0.58)	HDAC8MEN1KMT2ARAB9ANPC1
	SCHEMBL1353434	0.80	HDAC8 (0.55)	HDAC8MEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.