Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 17/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.42 |
| ▸ | CASP1 | P29466 | 6/20 | 0.42 |
| ▸ | CASP7 | P55210 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530775 | 0.94 | ALDH1A1 (0.47) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13530771 | 0.91 | CYP1A2 (0.41) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13529734 | 0.86 | CLK4 (0.42) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13530171 | 0.83 | ALDH1A1 (0.45) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13530768 | 0.82 | CYP1A2 (0.39) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13530929 | 0.82 | SGMS2 (0.40) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13529750 | 0.82 | PPIA (0.52) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL13530216 | 0.82 | CYP1A2 (0.47) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13530766 | 0.81 | AR (0.44) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR | |
| SCHEMBL13530371 | 0.81 | ALDH1A1 (0.44) | CYP1A2ALDH1A1CYP3A4CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9204653-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-01-23 | — | — | US | disclosed |
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2010-01-28 | — | — | US | disclosed |
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DPYD, DPM1, DDX5 | CYP1A2 430/4885ALDH1A1 1302/4885CYP3A4 207/4885 |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DPYD, DPM1, DDX5 | CYP1A2 430/4885ALDH1A1 1302/4885CYP3A4 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.