Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704781 | 1.00 | GAA (0.44) | GAAHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9623123 | 1.00 | GAA (0.44) | GAAHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11701365 | 0.98 | ALDH1A1 (0.43) | GAAHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1352156 | 0.92 | CYP1A2 (0.45) | GAAHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9623873 | 0.86 | CYP1A2 (0.46) | GAAHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25440571 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1LMNAHPGDALOX15 | |
| SCHEMBL1352439 | 0.84 | ALDH1A1 (0.47) | GAAHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6913720 | 0.79 | CYP1A2 (0.54) | GAAHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5474903 | 0.78 | ALDH1A1 (0.46) | HTTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL5474905 | 0.76 | ALDH1A1 (0.48) | GAAHTTSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368888-B1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SUMITOMO SEIKA CHEMICALS (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-20140012018-A1 | SULFOLANE COMPOSITION | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
| US-8436193-B2 | Method for manufacturing sulfolene compound and method for manufacturing sulfolane compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20110288307-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-2368888-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | Sumitomo Seika Chemicals CO. LTD. (JP) | 2011-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288307-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SULT1A1, STS, SULT2A1 | GAA 2347/4885HTT 1849/4885MAPK1 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.