Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.63 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.63 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465256 | 0.95 | LMNA (0.61) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL8733409 | 0.95 | LMNA (0.61) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL58833 | 0.95 | LMNA (0.61) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL6200177 | 0.95 | LMNA (0.61) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL16411213 | 0.93 | ALDH1A1 (0.63) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL6199890 | 0.93 | MEN1 (0.59) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL11042252 | 0.93 | LMNA (0.59) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL7342923 | 0.93 | LMNA (0.54) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL57081 | 0.91 | LMNA (0.56) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL7295478 | 0.91 | LMNA (0.55) | ALDH1A1LMNACYP3A4MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110284829-A1 | POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |