Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465256 | 1.00 | LMNA (0.61) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL58833 | 1.00 | LMNA (0.61) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL6200177 | 1.00 | LMNA (0.61) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL6199890 | 0.98 | MEN1 (0.59) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL7321345 | 0.95 | LMNA (0.65) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL7329668 | 0.95 | LMNA (0.65) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL1353239 | 0.95 | ALDH1A1 (0.63) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL11042252 | 0.95 | LMNA (0.59) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL6324073 | 0.95 | LMNA (0.55) | LMNAALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL57081 | 0.93 | LMNA (0.56) | LMNAALDH1A1CYP3A4MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |