SCHEMBL135365

SCHEMBL135365

CC1(C(=O)O)CC(C(=O)O)=NN1c1ccc(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
NOTUM Q6P988 2/20 0.41
RPA1 P27694 1/20 0.39
CYP11B2 P19099 1/20 0.39
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
OPRM1 P35372 3/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
MARS1 P56192 3/20 0.37
TSHR P16473 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MYC P01106 1/20 0.36
NR4A1 P22736 1/20 0.36
PDE5A O76074 1/20 0.35
AKR1C3 P42330 1/20 0.35
GRM5 P41594 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471146 1.00 LMNA (0.45) LMNANOTUMRPA1CYP11B2GABRA2
SCHEMBL29686790 1.00 LMNA (0.45) LMNANOTUMRPA1CYP11B2GABRA2
Butane SCHEMBL20916981 0.95 LMNA (0.42) LMNANOTUMRPA1CYP11B2GABRA2
Butane SCHEMBL677651 0.95 LMNA (0.42) LMNANOTUMRPA1CYP11B2GABRA2
SCHEMBL19698080 0.91 LMNA (0.41) LMNANOTUMRPA1CYP11B2GABRA2
Paraquat SCHEMBL2373860 0.89 LMNA (0.38) LMNANOTUMRPA1CYP11B2GABRA2
SCHEMBL6061258 0.86 GABRA2 (0.42) LMNAGABRA2GABRB2SMN1; SMN2MEN1
SCHEMBL29419101 0.85 GABRA2 (0.42) LMNANOTUMGABRA2GABRB2OPRM1
SCHEMBL30684851 0.85 GABRA2 (0.47) GABRA2GABRB2SMN1; SMN2MEN1MAPT
SCHEMBL3665939 0.85 GABRA2 (0.47) GABRA2GABRB2SMN1; SMN2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7139 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947350-B1 SUBSTITUTED 2-HETEROARYL AMINOBENZENES, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS BAYER AG (DE) 2026-05-27 EP claimed
EP-4742898-A1 HERBICIDE SAFENER COMBINATIONS AND COMPOSITIONS UPL Mauritius Limited (MU) 2026-05-20 EP claimed
EP-4742896-A1 HERBICIDE COMPOSITIONS COMPRISING MALONAMIDES AND SAFENERS FOR SELECTIVE WEED CONTROL IN CROPS BASF SE (DE) 2026-05-20 EP claimed
WO-2026088192-A1 METHOD FOR CONTROLLING WEED IN CEREAL CROPS ADAMA AGAN LTD. (IL) 2026-04-30 WO claimed
US-12610950-B2 Method for weed control in lawn or turf DISCOVERY PURCHASER CORPORATION (US) 2026-04-28 US claimed
US-20260096553-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2026-04-09 US claimed
US-20260076368-A1 HERBICIDAL COMPOSITION COMPRISING BIFENOX AND VLCFA INHIBITOR ADAMA AGAN LTD. (IL) 2026-03-19 US claimed
US-20260068883-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS ENKO CHEM, INC. (US) 2026-03-12 US claimed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
EP-4132937-B1 CO-CRYSTALS OF ANTIOXIDANTS AND ACTIVE INGREDIENTS AND USE OF ANTIOXIDANTS AS STABILIZER ADAMA AGAN LTD (IL) 2025-12-03 EP claimed
US-6555499-B1 Comprising 3-hydroxy-4-(4-methylphenyl)-5-oxo-pyrazoline, a safener (counter-agent, antidote) and oil additive to protect plants but not weeds against phytoxicity SYNGENTA CROP PROTECTION, INC. 2003-04-29 US claimed
EP-1301492-A1 NOVEL TETRAZOLE DERIVATIVES NIHON BAYER AGROCHEM K.K. (JP) 2003-04-16 EP claimed
WO-2003024221-A1 HERBICIDAL MIXTURES BASED ON 3-PHENYLURACILS BASF AKTIENGESELLSCHAFT (DE) 2003-03-27 WO claimed
EP-1209973-A1 HERBICIDE AGENT Syngenta Participations AG (CH) 2002-06-05 EP claimed
EP-1209972-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2002-06-05 EP claimed
US-20020055435-A1 Herbicidal mixtures INTELLECTUAL PROPERTY DEPARTMENT (DE) 2002-05-09 US claimed
WO-2002015694-A2 HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2002-02-28 WO claimed
WO-2002002536-A1 NOVEL TETRAZOLE DERIVATIVES BAYER CROPSCIENCE K.K. (DE) 2002-01-10 WO claimed
WO-2001017352-A1 HERBICIDE AGENT SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO claimed
WO-2001017351-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO claimed