Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686790 | 0.91 | LMNA (0.45) | LMNACYP11B2NOTUMOPRM1OPRD1 | |
| SCHEMBL135365 | 0.91 | LMNA (0.45) | LMNACYP11B2NOTUMOPRM1OPRD1 | |
| SCHEMBL471146 | 0.91 | LMNA (0.45) | LMNACYP11B2NOTUMOPRM1OPRD1 | |
| Butane SCHEMBL677651 | 0.87 | LMNA (0.42) | LMNACYP11B2NOTUMOPRM1OPRD1 | |
| Butane SCHEMBL20916981 | 0.87 | LMNA (0.42) | LMNACYP11B2NOTUMOPRM1OPRD1 | |
| SCHEMBL3665939 | 0.84 | GABRA2 (0.47) | ALDH1A1KDM4EGABRA2GABRB2MEN1 | |
| SCHEMBL30684851 | 0.84 | GABRA2 (0.47) | ALDH1A1KDM4EGABRA2GABRB2MEN1 | |
| Paraquat SCHEMBL2373860 | 0.81 | LMNA (0.38) | LMNACYP11B2NOTUMOPRM1OPRD1 | |
| SCHEMBL6061258 | 0.78 | GABRA2 (0.42) | LMNAALDH1A1KDM4EGABRA2GABRB2 | |
| Dcmu SCHEMBL2372306 | 0.78 | APEX1 (0.50) | LMNAOPRM1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170354146-A1 | SAFENING 4-AMINO-3-CHLORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)-5-FLUOROPYRIDINE-2-CARBOXYLIC ACID COMPOSITIONS IN BRASSICA SPECIES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170354148-A1 | SAFENED HERBICIDAL COMPOSITIONS CONTAINING HALAUXIFEN AND METHODS OF USE THEREOF IN BRASSICA SPECIES | DOW AGROSCIENCES LLC (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170354148-A1 | SAFENED HERBICIDAL COMPOSITIONS CONTAINING HALAUXIFEN AND METHODS OF USE THEREOF IN BRASSICA SPECIES | HACL2, BROX, HDHD5 | LMNA 3126/4885CYP11B2 1038/4885NOTUM 8/4885 |
| US-20170354146-A1 | SAFENING 4-AMINO-3-CHLORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)-5-FLUOROPYRIDINE-2-CARBOXYLIC ACID COMPOSITIONS IN BRASSICA SPECIES AND METHODS OF USE THEREOF | CIP2A, CASP2, BROX | LMNA 4612/4885CYP11B2 2633/4885NOTUM 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.