Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315805 | 0.90 | NPC1 (0.45) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2315072 | 0.87 | CCNA2 (0.46) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2315038 | 0.79 | CCNA2 (0.47) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL2314406 | 0.77 | MAPT (0.49) | HPGDALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL2315809 | 0.74 | NPC1 (0.43) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8694581 | 0.73 | CCNA2 (0.47) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3185793 | 0.73 | DRD4 (0.47) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8699740 | 0.73 | CHRM4 (0.42) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL330389 | 0.72 | ALDH1A1 (0.59) | HPGDALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL8698915 | 0.70 | KDM4E (0.47) | HPGDALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007046-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-01-21 | — | — | WO | disclosed |