Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599835 | 0.87 | SLC7A5 (0.43) | SLC7A5ALDH1A1LTA4H | |
| SCHEMBL13534741 | 0.87 | SLC7A5 (0.43) | SLC7A5ALDH1A1LTA4H | |
| SCHEMBL6956712 | 0.86 | PTGS2 (0.44) | ALDH1A1LTA4H | |
| SCHEMBL13849496 | 0.86 | PTGS2 (0.44) | ALDH1A1LTA4H | |
| SCHEMBL22458056 | 0.83 | TAAR1 (0.64) | SLC7A5TAAR1ALDH1A1 | |
| SCHEMBL1279049 | 0.83 | TAAR1 (0.64) | SLC7A5TAAR1ALDH1A1 | |
| SCHEMBL2658540 | 0.83 | TAAR1 (0.64) | SLC7A5TAAR1ALDH1A1 | |
| SCHEMBL1279586 | 0.81 | MEN1 (0.44) | ALDH1A1 | |
| SCHEMBL1279851 | 0.81 | MEN1 (0.44) | ALDH1A1 | |
| SCHEMBL6171672 | 0.81 | MTNR1A (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | SLC7A5 1918/4885TAAR1 4780/4885ALDH1A1 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.