Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355630 | 0.82 | HDAC2 (0.57) | HDAC3HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL13537152 | 0.80 | KDM4E (0.40) | NR1H4RAB9ASMN1; SMN2NAMPTLMNA | |
| SCHEMBL24169215 | 0.80 | HDAC3 (0.48) | NR1H4HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL13213695 | 0.80 | HDAC3 (0.47) | NR1H4HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL16504163 | 0.75 | HDAC3 (0.46) | NR1H4HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL22920719 | 0.73 | PGR (0.48) | NPC1RAB9ASMN1; SMN2TRPV1HDAC1 | |
| SCHEMBL24221611 | 0.72 | LMNA (0.48) | HDAC3HDAC11HDAC8HDAC6RAB9A | |
| SCHEMBL10136211 | 0.72 | ACE2 (0.67) | NPC1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11846340 | 0.72 | HTT (0.50) | NR1H4HDAC3HDAC8HDAC6NPC1 | |
| SCHEMBL23456131 | 0.72 | MAPT (0.46) | NR1H4NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649025-B2 | Composite ion-exchange membrane | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2010-01-19 | — | — | US | disclosed |