Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537206 | 0.90 | CNR2 (0.52) | CNR2CNR1ALDH1A1MAPTMEN1 | |
| SCHEMBL13537301 | 0.83 | ALDH1A1 (0.52) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL13537209 | 0.81 | CNR2 (0.41) | CNR2CNR1NPSR1 | |
| SCHEMBL13537208 | 0.80 | POLB (0.46) | CNR2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6042188 | 0.79 | CNR2 (0.70) | CNR2CNR1ALDH1A1MAPTMEN1 | |
| SCHEMBL3354060 | 0.78 | CNR2 (0.47) | CNR2CNR1ALDH1A1MAPTMEN1 | |
| SCHEMBL2050027 | 0.77 | CNR2 (0.67) | CNR2CNR1ALDH1A1MAPTMEN1 | |
| SCHEMBL1275593 | 0.76 | ALDH1A1 (0.46) | CNR2CNR1ALDH1A1MAPTMEN1 | |
| SCHEMBL2081693 | 0.76 | PRPS1 (0.58) | CNR2CNR1MAPTTSHRL3MBTL1 | |
| SCHEMBL2817707 | 0.74 | ALDH1A1 (0.50) | CNR2CNR1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |