Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357593 | 0.91 | CNR1 (0.47) | CNR2CNR1CDK2ALDH1A1MAPT | |
| SCHEMBL3354160 | 0.84 | ALDH1A1 (0.50) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL3354062 | 0.84 | KMT2A (0.41) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL3352886 | 0.81 | MAPT (0.42) | CNR2ALDH1A1MAPTKMT2A | |
| SCHEMBL3352477 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2846714 | 0.79 | CDK2 (0.56) | CDK2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11524512 | 0.79 | HTT (0.44) | CNR2CDK2ALDH1A1MAPTKMT2A | |
| SCHEMBL14406114 | 0.78 | SERPINE1 (0.53) | CNR2CNR1CDK2ALDH1A1MAPT | |
| SCHEMBL13537299 | 0.78 | CNR2 (0.52) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL3352610 | 0.78 | F2RL3 (0.39) | ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |